Radioligand Therapy: Redefining Precision in Cancer Diagnosis and Therapy

In the evolving landscape of oncology, Radioligand Therapy (RLT) is emerging as a transformative approach that combines the power of diagnostics and therapeutics into a single, highly targeted modality. At Infosys, we recognize the potential of RLT to revolutionize cancer care and are committed to enabling this shift through digital innovation and strategic partnerships.

Why Pharma Companies Are Investing in RLT Imaging Systems
  • Strategic Control: Integrating diagnostics and therapy enhances clinical outcomes and commercial scalability.
  • Data Ownership: Proprietary imaging data enables deeper insights into patient response and treatment optimization.
  • Innovation Enablement: RLT systems support companion diagnostics, clinical trials, and pipeline expansion.
How is RLT’s mode of action?

RLTs consist of two key components:

  • A radioactive particle (which can be customized for different therapeutic needs)
  • A ligand that binds to specific markers on cancer cells

The ligand guides the radioisotope to target cancer cells, even those that have metastasized. This mechanism allows for precise destruction of tumor cells and components of the tumor microenvironment (TME), while sparing healthy tissue—ultimately aiming to improve quality of life for patients.

Why is RLT a Game Changer?

Radioligand Imaging (RLT) is transforming cancer care by shifting the focus from generalized treatment to precision-guided, molecular-level intervention. Unlike traditional imaging that only shows anatomical structures.

1.      Theranostic Capability
Combines diagnosis and therapy in one step—targeting and treating cancer simultaneously.

2.      Highly Targeted Mechanism
Radioligands bind specifically to cancer cells, delivering radiation directly to tumors while sparing healthy tissue.

3.      Functional Imaging Insights
Goes beyond anatomy to reveal blood flow, metabolism, and receptor activity for early detection and monitoring.

4.      Enhanced Safety and Efficacy
Fewer side effects and better outcomes, especially for metastatic or resistant cancers.

5.      Personalized Treatment Planning
Enables tailored therapy by assessing tumor burden and response in real time.

How Infosys Supports RLT Transformation

At Infosys, we empower pharma and healthcare organizations to scale RLT adoption through:

  • Digital Infrastructure: Building platforms for data integration, AI-driven imaging analytics, and clinical decision support.
  • Partner Ecosystem Enablement: Orchestrating vendor ecosystems to accelerate RLT deployment and operational excellence.
  • Regulatory & Compliance Support: Ensuring imaging systems meet global standards for safety, efficacy, and data governance.
  • Change Management: Driving clinical adoption, training, and workflow integration across oncology networks.
Conclusion

Radioligand Imaging is not just a technological advancement—it’s a paradigm shift in oncology care. As pharma companies embrace this precision-driven approach, Infosys stands ready to support the transformation with cutting-edge digital solutions, strategic consulting, and deep domain expertise.

 

Author Details

Neha Prasad

Neha Prasad is a Senior Consultant at Infosys Consulting with 16 years of expertise with Clinical trials project management ,Clinical systems, and medical services. Neha Has Successfully executed projects from Kick-off to Go-Live through Planning, Execution, Testing, Change Management & Release Co-ordination. She has led global teams and managed end-to-end product lifecycles, integrating AI and analytics to optimize clinical operations.

Yash Parte

Life Sciences Consultant with 3+ years of experience across clinical trial operations and management, regulatory documentation, and application management support. Skilled in process optimization, stakeholder coordination, and regulatory compliance using tools like Veeva Vault and CTMS. Adept at managing change, incident, and documentation workflows through structured methodologies, ensuring delivery excellence and audit readiness in complex, cross-functional environments

Shubhangi Tanwar

Shubhangi is a Clinical technology specialist and business analyst with 6+ years of healthcare experience including hands-on expertise in Veeva CTMS, e-TMF and oracle systems, adept in using PM and ITSM tools (JIRA, Trello, Confluence, ServiceNow) and well versed in operational procedures including service request, change, incident and inventory management.

Naveen Nirmal Kumar Devaraj

A Principal consultant with depth of domain & IT experience specializing in R&D Transformation and Capability Building. I partner with pharmaceutical and life sciences organizations to drive innovation, operational excellence, and sustainable growth. With a deep understanding of the complexities in drug development, clinical research, pharmacovigilance, and regulatory affairs, I help organizations modernize their R&D processes and build robust capabilities that align with evolving industry standards and technological advancements.

Supriya Sahu

Supriya is Driving the next wave of innovation in Clinical R&D. As a Principal Consultant at Infosys Consulting, Supriya specializes in digital transformation, ensuring compliance and excellence through deep knowledge of Quality Assurance and managing complex Regulatory Inspections and Vendor Ecosystems. My current mandate is clear: deploy GenAI automation across the clinical research lifecycle to deliver unprecedented speed and quality. Action-oriented leader turning cutting-edge technology into bottom-line performance.

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